A Model System To Elucidate The Origin Of Protein Misfolding Neurodegenerative Diseases

November 28 2008

Amyotropic lateral sclerosis (ALS) is a neurodegenerative disease linked to the misfolding and aggregation of the dimers of the enzyme superoxide dismutase (SOD1). Other neurodegenerative disorders like Alzheimer's disease, Creutzfeld-Jakob disease and Parkinson's disease are also associated with protein misfolding and aggregation.

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    A group of diseases causing muscle weakness at birth. Several defined genetic mutations cause muscles to break down faster than they can repair or grow. A child with CMD may have various neurological or physical impairments. Some children never gain the ability to walk, while others lose the ability as they grow older. Learn more...
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