Bax Inhibition

Dr. Miller’s lab at BBRI, showed that inhibition of protein called Bax, improved life span in mouse models with merosin deficient CMD. The Bax protein is involved in upregulating apoptosis, programmed cell death.

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  • Congenital Muscular Dystrophy

    A group of diseases causing muscle weakness at birth. Several defined genetic mutations cause muscles to break down faster than they can repair or grow. A child with CMD may have various neurological or physical impairments. Some children never gain the ability to walk, while others lose the ability as they grow older. Learn more...

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