HSPH-Led Team Discovers Protective Cellular Process In ALS Disease In Mice, Hinting At New Therapeutic Approach

September 17 2009

When Harvard School of Public Health (HSPH) scientists disabled a specific protein in mice that were genetically prone to develop ALS (Lou Gehrig's disease), they expected -- based on previous work -- to hasten the onset of the paralyzing, lethal disorder. What they found was the reverse.

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    A group of diseases causing muscle weakness at birth. Several defined genetic mutations cause muscles to break down faster than they can repair or grow. A child with CMD may have various neurological or physical impairments. Some children never gain the ability to walk, while others lose the ability as they grow older. Learn more...
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